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Patient guide · Weight

Before you start a GLP-1: what to know

Semaglutide and tirzepatide get most of the questions at the front desk. Here is who they are approved for, what the FDA warns about, and how Dr. Wood decides.

What a GLP-1 does

GLP-1 is one of the hunger hormones Dr. Wood describes in why obesity is a disease: it helps tell the brain you have eaten enough. GLP-1 medications act on that same signal.

Who they are approved for

The FDA approved Zepbound (tirzepatide) for chronic weight management in adults with a body mass index of 30 or more, or 27 or more with at least one weight-related condition such as high blood pressure, type 2 diabetes or high cholesterol, used together with a reduced-calorie diet and more activity (FDA). Wegovy (semaglutide) and Saxenda (liraglutide) carry the same adult criteria on their labels (Wegovy label; Saxenda label).

What the FDA warns about

The FDA has warned about dosing errors with compounded semaglutide, and about counterfeit and fraudulent GLP-1 products (FDA). A medicine this strong belongs with a physician who knows your history and checks your labs.

How Dr. Wood decides

  • Not on request. Total Body Renewal does not prescribe weight-loss medication because someone asks for it. It follows a visit, an exam and your labs.
  • One option among several. GLP-1 therapy is one of the FDA-approved medicines Dr. Wood weighs; another may suit you better, or none at all.
  • Never alone. Medication sits inside a plan with a written nutrition plan, monthly visits and progress labs every 8 to 12 weeks.

What to expect from the result

The aim is health first. Losing 5% to 10% of your starting weight may lower blood sugar, blood pressure and triglycerides (NIDDK), and that is why progress is measured in labs and a body composition scan as well as on the scale. To find out whether a GLP-1 fits you, start with a new-patient visit for medical weight management.

Questions

Questions about this guide

Who qualifies for Wegovy or Zepbound?

Adults with a BMI of 30 or more, or 27 or more with a weight-related condition such as high blood pressure, type 2 diabetes or high cholesterol, according to the FDA approvals — alongside diet and activity.

Is compounded semaglutide safe?

The FDA has warned about dosing errors with compounded semaglutide and about counterfeit and fraudulent GLP-1 products. Any GLP-1 should come through a physician who has examined you and checks your labs.

Can I get a GLP-1 at my first visit?

Not automatically. Dr. Wood reviews your history, examines you and orders labs first; medication is considered once she has the results, and only if it suits you.

How does a GLP-1 medication help with weight loss?

It acts on the same signal as GLP-1, one of the hunger and fullness hormones Dr. Wood describes, which is why it is weighed alongside your labs and history rather than prescribed on request.

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